There have been reports of crashes launching HighDesign R6.0.2 on macOS Monterey. The issue does not occur consistently and has been corrected already for the upcoming update.
If you need to use HighDesign on macOS Monterey, the workaround is to temporarily disable the Internet connection before launching HighDesign and restore it when the application is open.
This is just a temporary workaround until the release of the new update, which is right around the corner anyway.